Great post into IBM's use of podcasts (thanks to Paul Gillin). Senior management have sensibly not tried to micro manage the process but allowed employees the ability to drive the project forward.
We do all the production work for internal podcasts by another IT multi-national. They use them in the UK for two reasons - logistics and knowledge sharing. Their management at European level uses podcasts to get monthly information and business updates out to the team who are based in offices and 'home offices' across multiple countries. Whilst a podcast can never replace a 'face-to-face' communication it has far more impact than an e-mail. The other use is knowledge sharing. With teams working on projects that may not see the light of day for a while it is easy for parts of the workforce to become detached with what is happening. Podcasts are a great way for these projecst to get some visibility and if employees are interested they can keep in touch with progress.